Coagulase negative staphylococcal sepsis in neonates: do we need to adapt vancomycin dose or target?
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منابع مشابه
Coagulase negative staphylococcal sepsis in neonates: do we need to adapt vancomycin dose or target?
BACKGROUND Despite differences in types of infection and causative organisms, pharmacokinetic-pharmacodynamic (PKPD) targets of vancomycin therapy derived from adult studies are suggested for neonates. We aimed to identify doses needed for the attainment of AUC/MIC > 400 and AUC/MIC > 300 in neonates with sepsis and correlate these targets with recommended doses and treatment outcome. METHODS...
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ژورنال
عنوان ژورنال: BMC Pediatrics
سال: 2016
ISSN: 1471-2431
DOI: 10.1186/s12887-016-0753-0